Forbes released its 'World's Billionaires List' for 2022, which includes 32 U.S. billionaires who made their fortunes in the health care industry.

Forbes' 36th annual ranking of the world's billionaires identified 2,668 individuals—87 fewer than last year's rankings. In total, 2022's billionaires are worth a collective $12.7 trillion—a $400 billion decrease from 2021. 

According to Forbes, the "war, pandemic, and sluggish markets," had an impact on billionaires this year.

The 'Most Influential’ health care leaders, according to TIME

Overall rankings

Overall, the wealthiest billionaires on Forbes' list are:

1. Elon Musk, co-founder and CEO and founder of SpaceX and Tesla, with $219 billion

2. Jeff Bezos, Amazon founder and executive chair, with $171 billion

3. Bernard Arnault, founder, CEO, and chair of LVMH, and his family, with $158 billion

Billionaires in the health care industry

Forbes divided the billionaires on its list into several categories, including those whose fortunes were made primarily in the health care industry. The health care list did not include billionaires who made their fortunes in other industries but who have since ventured into health care, such as Bezos.

The U.S. billionaires included in Forbes' health care category, in order of 2022 net worth, are:

73. Thomas Frist Jr. and family, co-founder of Hospital Corp. of America, with $21.8 billion

177. Carl Cook, CEO of medical device manufacturer Cook Group, with $11.1 billion

235. Li Ge, cofounder and chair of WuXi AppTec, a global research and development and manufacturing services company that provides support to the pharmaceutical, biotech, and medical device industries, with $8.8 billion

324. Patrick Soon-Shiong, who invented Abraxane, a drug used to fight pancreatic cancer, with $7.3 billion

330. Reinhold Schmieding, founder of orthopedic surgical tools company, Arthrex, with $7.2 billion

363. Ronda Stryker, director of medical equipment and software company Stryker Corp., with $6.8 billion

490. John Brown, who ran Stryker Corp. for 32 years before stepping down as chair in 2009, with $5.4 billion

687. Jon Stryker, whose grandfather founded Stryker Corp., with $4.2 billion

728. Hao Hong, chairman of Asymchem Laboratories, which provides pharmaceutical outsourcing services, with $4 billion

984. Pat Stryker, founder of Bohemian Foundation, which supports music, community, global, and civic programs, and whose grandfather founded Stryker Corp., with $3.1 billion

1238. Stewart Rahr, who expanded pharmaceutical distributor Kinray, before selling it to Cardinal Health in 2021 for $1.3 billion, with $2.5 billion

1292. Jeff Tangney, who cofounded Doximity, which is often referred to as a "LinkedIn for Doctors," with $2.4 billion

1341. Osman Kibar, founder and CEO of biotech firm Samumed, with $2.3 billion

1397. Phillip Frost, a long-time health care investor and founder, who now runs diagnostics-maker Opko Health, with $2.2 billion

1445. Alice Schwartz, who launched Bio-Rad Laboratories with her husband in 1952, with $2.1 billion

1445. Timothy Springer, Harvard Medical School immunologist and professor of biological chemistry and molecular pharmacology, with $2.1 billion

1445. Amy Wyss, whose father founded Synthes, a medical equipment firm where she worked for years, with $2.1 billion

1513. Robert Duggan, an entrepreneur who led the 2015 sale of biotech firm Pharmacyclics to AbbVie for $21 billion in cash and stock, with $2 billion

1645. Gary Michelson, a retired orthopedic and spinal surgeon with more than 340 U.S. patents for orthopedic and spinal surgery instruments, with $1.8 billion

1645. David Paul, Globus Medical founder and executive chair, with $1.8 billion

1729. Noubar Afeyan, Flagship Pioneering founder and CEO, with $1.7 billion

1729. Keith Dunleavy and family, founder of cloud-based health care data analytics company Inovalon, with $1.7 billion

1729. Janes Leininger, also known as "Doctor Jim," who founded medical devices company Kinetic Concepts, with $1.7 billion

1818. Randal Kirk, chair of venture capital and private equity firm Third Security LLC, with $1.6 billion

1818. Robert Langer, a scientist and professor at the Massachusetts Institute of Technology, who leads the Langer Lab, with $1.6 billion

1929. Alan Miller and family, Universal Health Services founder, with $1.5 billion

2076. George Yancopoulos, Regeneron chief scientific officer, with $1.4 billion

2190. Forrest Preston, founder of Life Care Centers of America, with $1.3 billion

2190. August Troendle, Medpace president and CEO, with $1.3 billion

2324. Leonard Schleifer, Regeneron cofounder and CEO, with $1.2 billion

2448. Lou Boliang, Pharmaron cofounder and chair, with $1.1 billion

2448. John Oyler, cofounder and CEO of biotech company BeiGene, with $1.1 billion

(Forbes 2022 "World's Billionaires List," accessed 4/13; Henderson, MedPage Today, 4/12)