To combat staffing shortages, health systems are increasingly turning to virtual nursing as a solution to ease the burden on their staff. This guide identifies the top four common concerns the nursing workforce has about broad implementation of virtual nursing: decreased human touch in healthcare, investment in technology instead of the workforce, increased staffing ratios, and worsened workflow inefficiencies. For each of the concerns, we provide strategies for leaders to address these issues and a conversation guide to help discuss these concerns with their staff.